ADMET	Absorption: distribution, metabolism, excretion and toxicity
BBB	Blood brain barrier
CFTR	Cystic fibrosis transmembrane conductance regulator
ECD	Extracellular domain
ECDGC-C	Extracellular domain of Guanylyl cyclase c
ETEC	Enterotoxigenic Escherichia coli
GC-C	Guanylyl cyclase c
GCs	Guanylyl cyclases
HBA	Hydrogen bond acceptor
HBD	Hydrogen bond donor
HIA	Human Intestinal Absorption
IBD	Inflammatory bowel disease
IBS	Irritable bowel syndrome
MLCK	Myosin light chain kinase
NHE3	Na+/H+ exchanger isotype 3
NPR-A	atrial brain natriuretic peptide
NPR-B	brain natriuretic peptide
NPR-C	Natriuretic Peptide Receptor-C
PDB	Protein Data Bank
P-gp	P- glycoprotein
PSA	Polar surface area
RCSB	Research Collaboratory for Structural Bioinformatics
RMSD	Root mean square deviation
RMSF	Root mean square fluctuation
STa	Heats stable enterotoxin
TJ	Tight junction