Table 6.
ADMET Predicted Profile (Toxicity).
| Ligand | AMES toxicity | Carcinogenicity | Rat Acute Toxicity (mol/kg) |
|---|---|---|---|
| Kurchessine | Non AMES toxic | Non-carcinogens | 2.5575 |
| Conessine | Non AMES toxic | Non-carcinogens | 2.6198 |
| Isoconessimine | Non AMES toxic | Non-carcinogens | 2.6781 |
| Pubescine | Non AMES toxic | Non-carcinogens | 2.9255 |
| Holadienine | Non AMES toxic | Non-carcinogens | 2.5022 |
| Holanamine | Non AMES toxic | Non-carcinogens | 2.1900 |
| Conessimine | Non AMES toxic | Non-carcinogens | 2.6437 |
| Holadysenterine | Non AMES toxic | Non carcinogens | 2.4973 |
| Kurchine | Non AMES toxic | Non carcinogens | 2.6781 |
| Loperamide | Non AMES toxic | Non carcinogens | 3.6560 |