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. 2021 Jul 11;10(7):1753. doi: 10.3390/cells10071753

Figure 5.

Figure 5

Possible complexes involved in telomere replication and T-loop-based capping. Fork rescue has been shown to involve TRF1 [13], most probably as a TRF2-independent complex [65], and TRF2 independently of TRF1 [14,92]. On the other hand, T-loop-dependent capping involves TRF2 [50], and the single-strand overhang dynamics are regulated by TPP1-POT1 [25], most probably as a TRF1-independent complex.