Table 3.
Descriptive analysis of discovery cohort.
| Variables (Number of Observations) |
Controls (n = 1003) |
Cases (n = 141) |
p-Value | OR (95% IC) |
|---|---|---|---|---|
| Age (n= 1142) | 75 ± 16 | 77 ± 12 | 6.70 × 10−2 | |
| Sex (n = 1144), male | 55% (548/1003) | 52% (73/141) | 5.29 × 10−1 | 0.89 (0.62–1.29) |
| HTN (n = 1138) | 64% (634/998) | 65% (91/140) | 7.79 × 10−1 | 1.07 (0.73–1.58) |
| DM (n = 1143) | 22% (225/1002) | 30% (42/141) | 5.64 × 10−2 | 1.46 (0.97–2.19) |
| DLP (n = 821) | 38% (279/728) | 37% (34/93) | 8.21 × 10−1 | 0.93 (0.57–1.48) |
| AF (n = 1140) | 37% (299/999) | 38% (53/141) | 7.93 × 10−2 | 1.41 (0.96–2.07) |
| SH (n = 788) | 21% (148/698) | 18% (16/90) | 3.93 × 10−1 | 0.8 (0.42–1.44) |
| NIHSS (n = 1141) | 14 ± 11 | 17 ± 9 | 4.11 × 10−4 | |
| mRS (n = 587) | 0 ± 1 | 0 ± 1 | 1.84 × 10−2 | |
| Gly (n = 1104) | 119 ± 44 | 127 ± 49 | 1.02 × 10−1 | |
| SBP (n = 705) | 153 ± 35 | 158 ± 37 | 2.50 × 10−1 | |
| DBP (n = 731) | 80 ± 20 | 80 ± 20 | 4.47 × 10−1 | |
| IA (n = 708) | 5% (28/620) | 13% (11/88) | 5.12 × 10−3 | 3.01 (1.30–6.55) |
| TM (n = 336) | 6% (17/286) | 0% (0/50) | 8.72 × 10−2 | 0 (0–1.36) |
| CES (n = 1115) | 46% (451/977) | 55% (76/138) | 5.57 × 10−2 | 1.43 (0.98–2.08) |
| LAS (n = 1115) | 20% (193/977) | 9% (11/138) | 3.91 × 10−4 | 0.35 (0.17–0.67) |
| SVO (n = 1115) | 1% (12/977) | 1% (2/138) | 6.88 × 10−1 | 1.18 (0.13–5.40) |
OR (95% IC): odds ratio (95% confidence interval -CI-). HTN: hypertension, DLP: dyslipidemia, AF: atrial fibrillation, SH: smoking habits, NIHSS: National Institutes of Health Stroke Scale, mRS: modified Rankin Score, Gly: initial glycaemia, SBP: systolic blood pressure, DBP: diastolic blood pressure; IA: intra-arterial fibrinolysis, TM: mechanical thrombectomy, CES: cardioembolic stroke, LAS: large artery atherosclerosis stroke, SVO: small vessel occlusion stroke. For quantitative variables, information is expressed as median ± interquartile range. For categorical variables in frequency (%). Variables significantly associated with PH (p-value < 0.05) are highlighted in bold.