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Effects of metformin on relative mRNA expression (D–F) and activity (desaturation index) (A–C) of the desaturases SCD-1, FADS-1 and FADS-2 in myocardium of Wistar control (W) and hereditary hypertriglyceridemic (HHTg) rats. Data are mean ± SEM; n = 8 for each group. Significance was determined using two-way ANOVA and Fisher’s LSD post-hoc test (* denotes p < 0.05; ** denotes p < 0.01; *** denotes p < 0.001).
