Table 4.
Sensitivity and specificity (%) vs CH for different MTA score thresholds
| MTA cut-off | Sensitivity | Specificity | ||
|---|---|---|---|---|
| AD | SVD | Mixed | ||
| ≤ 74 years | ||||
| N | 77 | 19 | 26 | 99 |
| 0.5 | 96.1 | 89.5 | 92.3 | 36.4 |
| 1.0 | 81.8 | 84.2 | 80.8 | 67.7 |
| 1.5 | 66.2 | 47.4 | 53.8 | 97.0 |
| 2.0 | 48.1 | 26.3 | 42.3 | 100 |
| ≥ 75 years | ||||
| N | 21 | 6 | 25 | 6 |
| 0.5 | 95.2 | 83.3 | 100 | 0 |
| 1.0 | 90.5 | 66.7 | 88.0 | 16.7 |
| 1.5 | 76.2 | 50.0 | 72.0 | 66.7 |
| 2.0 | 61.9 | 16.7 | 48.0 | 100 |
MTA cut-off indicates lowest pathological mean MTA score (average right + left)
Dementia subtypes other than AD, vascular dementia and mixed dementia not shown (n (≤ 74 years) = 33, n (≥ 75 years) = 7)
AD Alzheimer’s disease, CH Cognitively healthy, Mixed Mixed dementia, MTA Medial temporal lobe atrophy, SVD Subcortical vascular dementia