Table 1.
Clinical and pathological characteristics of the study population.
| Characteristics | Patients n 282 |
|
|---|---|---|
| Age, years, median (IQR) | 69.5 (61.9–75.0) | |
| Gender, male, n (%) | 167 (59.2) | |
| CA 19.9, U/mL, median (IQR) | 209.0 (33.3–1418.3) | |
| Type of BTC, n (%) | ICC | 129 (45.7) 94 (33.3) 22 (7.8) 37 (13.1) |
| PCC | ||
| DCC | ||
| GBC | ||
| Jaundice, n (%) | 127 (45.0) | |
| Preoperative Biliary Drainage (PBD), n (%) | 113 (40.1) | |
| Preoperative Chemotherapy, n (%) | 12 (4.3) | |
| Portal Vein Embolization (PVE), n (%) | 9 (3.2) | |
| Tumor size, mm, median (IQR) | 50 (30–60) | |
| Type of Surgery, n (%) | Atypical Liver Resection | 5 (1.8) |
| Segmentectomy | 13 (4.6) | |
| Bisegmentectomy | 60 (21.3) | |
| Left Hepatectomy | 79 (28.0) | |
| Right Hepatectomy | 53 (18.8) | |
| Mesohepatectomy | 7 (2.5) | |
| Left Trisectionectomy | 10 (3.5) | |
| Right Trisectionectomy | 7 (2.5) | |
| Other Major Hepatectomy | 7 (2.5) | |
| Pancreaticoduodenectomy | 23 (8.2) | |
| Common Bile Duct Resection | 14 (5.0) | |
| Cholecystectomy | 1 (0.3) | |
| Hepatoduodenectomy | 3 (1.1) | |
| Extent of Hepatectomy, n (%) | Minor | 80 (28.4) |
| Major | 164 (58.2) | |
| n/a | 38 (13.4) | |
| Biliary Resection, n (%) | 168 (59.6) | |
| Vascular resection, n (%) | 28 (9.9) | |
| AJCC 8th Ed. T Stage, n (%) | T1-2 | 129 (45.7) |
| T3-4 | 153 (54.3) | |
| AJCC 8th Ed. N Stage, n (%) | N0 | 153 (54.3) |
| N1-2 | 129 (45.7) | |
| Histologic Grading | G1-2 | 196 (69.5) |
| G3-4 | 73 (25.9) | |
| n/a | 13 (4.6) | |
| Macrovascular invasion, n (%) | 74 (26.2) | |
| Microvascular invasion, n (%) | 199 (70.6) | |
| Radicality of Surgery, n (%) | R0 | 193 (68.4) |
| R1 | 89 (31.6) | |
| Severe Morbidity (Clavien–Dindo ≥ 3), n (%) | 62 (22.0) | |
| Postoperative mortality, n (%) | 5 (1.8) | |
| Hospital stay, days, median (IQR) | 12 (7–19) | |
| Postoperative chemotherapy | 181 (64.2) | |
IQR, interquartile range; AJCC, American Joint Committee against Cancer.