Table 4.
ROC curves analysis of the inflammatory-based and nutritional prognostic factors.
| Prognostic Marker | Overall Survival AUC * | Sensitivity | Specificity | Youden Index | AIC § | Max K–S # |
|---|---|---|---|---|---|---|
| 12 months | ||||||
| GPS | 0.706 | 0.714 | 0.722 | 0.436 | 104.650 | 0.436 |
| mGPS | 0.642 | 0.500 | 0.789 | 0.289 | 99.128 | 0.289 |
| PI | 0.651 | 0.571 | 0.738 | 0.309 | 98.870 | 0.310 |
| NLR | 0.558 | 0.536 | 0.527 | 0.063 | 101.090 | 0.159 |
| PLR | 0.603 | 0.536 | 0.629 | 0.165 | 99.846 | 0.164 |
| LMR | 0.590 | 0.714 | 0.477 | 0.191 | 99.310 | 0.191 |
| PNI | 0.664 | 0.750 | 0.582 | 0.332 | 100.732 | 0.332 |
| 24 months | ||||||
| GPS | 0.604 | 0.471 | 0.742 | 0.213 | 129.729 | 0.213 |
| mGPS | 0.555 | 0.314 | 0.794 | 0.108 | 128.051 | 0.108 |
| PI | 0.561 | 0.386 | 0.742 | 0.128 | 127.751 | 0.128 |
| NLR | 0.577 | 0.571 | 0.555 | 0.126 | 129.477 | 0.126 |
| PLR | 0.603 | 0.600 | 0.600 | 0.200 | 130.853 | 0.193 |
| LMR | 0.623 | 0.671 | 0.548 | 0.219 | 127.393 | 0.235 |
| PNI | 0.608 | 0.629 | 0.606 | 0.235 | 130.117 | 0.220 |
| 36 months | ||||||
| GPS | 0.602 | 0.439 | 0.776 | 0.215 | 131.604 | 0.214 |
| mGPS | 0.555 | 0.306 | 0.806 | 0.112 | 127.562 | 0.112 |
| PI | 0.559 | 0.378 | 0.745 | 0.123 | 127.022 | 0.122 |
| NLR | 0.576 | 0.551 | 0.541 | 0.092 | 129.026 | 0.092 |
| PLR | 0.563 | 0.480 | 0.643 | 0.123 | 128.589 | 0.122 |
| LMR | 0.652 | 0.633 | 0.633 | 0.266 | 126.807 | 0.265 |
| PNI | 0.611 | 0.643 | 0.571 | 0.214 | 128.579 | 0.184 |
GPS, Glasgow Prognostic Score; mGPS, modified Glasgow Prognostic Score; PI, Prognostic Index; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; LMR, lymphocyte to monocyte ratio; PNI, prognostic nutritional index. AUC, area under curve, * The AUC values reported were cathegorized/dichotomized based on optimal cut-off identified by ROC curves analysis; § Akaike Information Criterion; # maximal Statistics Kolmogorov–Smirnov.