Table 1.
Integrins involved in the normal eye and eye diseases.
| Part of the Eye/Disease | Integrins |
|---|---|
| Cornea/ | |
| normal expression | α2β1, α3β1, αVβ5, α6β4 |
| injury | αVβ6 |
| healing process of the injury | α2, β1 |
| corneal lymphangiogenesis | α5β1 |
| cicatricial pemphigoid | α6β4 |
| epidemic keratoconjunctivitis | αVβ1, αVβ5, α3β1 |
| Conjunctiva and cornea/ | |
| allergic conjunctivitis | α4β1, α4β7, αMβ2, αLβ2 |
| epidemic keratoconjunctivitis | αVβ1, αVβ5, α3β1 |
| dry eye disease | αLβ2 |
| COVID-19 | αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α5β1, α8β1, αIIbβ3 |
| Lens/ | |
| normal development | α3β1, α6β1, α6β4, α1β1, α2β1, α5β1, αVβ3 |
| Cataract | αVβ5, αVβ6, αVβ3 |
| Trabecular meshwork or optic nerve head/ | |
| Glaucoma | αVβ3 |
| Retina/ | |
| diabetic retinopathy | αLβ2 |
| retinopathy of prematurity | αVβ3 |
| regeneration of the axons of the optic nerve | α9β1 |
| sclera/ | |
| myopia | α1, β1 |