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. 2021 Jul 9;12(7):1057. doi: 10.3390/genes12071057

Table 3.

Patients’ characteristics at last follow-up (n = 20).

Parameter Absolute Frequency (%) p Value
No Nephropathy Nephropathy
Gender Male 4 (20) 4 (20) 0.714
Female 5 (25) 7 (35)
DST No 4 (20) 2 (10) 0.336
Yes 5 (25) 9 (45)
ACEI No 8 (40) 1 (5) 0.001
Yes 1 (5) 10 (50)
Diabetes No 8 (40) 8 (40) 0.591
Yes 1 (5) 3 (15)
Parameter Median (25–75%) p Value
No Nephropathy Nephropathy
Age (years) 32.0 (27.3–48.8) 58.9 (47.9–65.8) 0.001
UPCR (g/mol) 9.60 (8.25–10.9) 32.2 (12.2–95.2) * 0.001
UACR (g/mol) 0.85 (0.60–1.55) * 7.80 (2.35–81.5) ** 0.001
D-prot (g/day) 0.11 (0.09–0.16) 0.20 (0.14–1.41) 0.067
S-Cr (µmol/L) 63.0 (55.5–72.5) 80.0 (58.0–87.0) 0.175
U-Cr (µmol/L) 5489 (3180–9601) * 5441 (3247–10,802) 0.657
eGFR (mL/min/1.73 m2) 116.0 (99.5–119.5) 81.0 (64.0–95.0) 0.001
GFR slope (mL/min/year) −0.71 (−2.30–1.87) −2.17 (−4.34–−1.28) 0.080

DST, disease specific therapy; ACEI, angiotensin-converting enzyme inhibitor; UPCR, urinary protein-to-creatinine ratio; UACR, urinary albumin-to-creatinine ratio; D-prot, daily proteinuria; S-Cr, serum creatinine; U-Cr, urinary creatinine; eGFR, estimated glomerular filtration rate; GFR, glomerular filtration rate. Bold font indicates statistical significance. * One datum is missing. ** Two data are missing.