Table 8.

Fold changes in the expression of miRNAs in (a) all patients (n = 14), (b) patients without nephropathy (n = 6), and (c) patients with Fabry nephropathy (n = 8) in samples collected approximately 10 years apart.

(a) All Patients	Parameter	Median (25–75%)		p Value
		10 Years Ago	Last Follow-up
	hsa-miR-200a-3p	1.49 (1.36–2.02)	2.81 (1.99–4.13) *	0.001
	hsa-miR-29a-3p	0.66 (0.34–0.84)	1.79 (0.98–2.88)	0.001
	hsa-miR-30b-5p	5.19 (3.59–11.2)	9.29 (6.48–10.6)	0.048
	hsa-miR-23a-3p	1.55 (1.05–1.93)	1.29 (0.79–1.78)	0.510
	hsa-miR-34a-5p	0.17 (0.10–0.27)	0.12 (0.07–0.19)	0.826
(b) Without Nephropathy	Parameter	Median (25–75%)		p Value
		10 Years Ago	Last Follow-up
	hsa-miR-200a-3p	1.54 (1.33–1.95)	3.05 (2.21–4.76)	0.028
	hsa-miR-29a-3p	0.71 (0.25–1.00)	1.78 (1.00–2.70)	0.028
	hsa-miR-30b-5p	7.07 (3.35–10.0)	8.31 (6.49–11.7)	0.028
	hsa-miR-23a-3p	1.58 (0.93–1.70)	1.34 (0.79–2.17)	0.917
	hsa-miR-34a-5p	0.12 (0.08–0.27)	0.12 (0.09–0.22)	0.600
(c) With Nephropathy	Parameter	Median (25–75%)		p Value
		10 Years Ago	Last Follow-up
	hsa-miR-200a-3p	1.49 (1.35–2.18)	2.58 (1.86–4.09) *	0.018
	hsa-miR-29a-3p	0.60 (0.41–0.88)	1.89 (0.97–3.08)	0.012
	hsa-miR-30b-5p	5.02 (3.88–13.0)	9.63 (5.68–10.7)	0.401
	hsa-miR-23a-3p	1.32 (1.07–2.09)	1.29 (0.76–1.58)	0.161
	hsa-miR-34a-5p	0.21 (0.10–0.35)	0.12 (0.05–0.22)	0.575

Bold font indicates statistical significance. * One datum is missing.