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. 2021 Jul 20;13(14):3639. doi: 10.3390/cancers13143639

Table 1.

Different abundance proteins identified by mass spectrometry in EC compared to the control serum.

Accession Number Spot Number Protein Description Gene Symbol Protein Score Fold Change * p-Value
P10909 10 Clusterin CLU 353.36 2.25 0.014
P01008 15 Antithrombin SERPINC1 1165.24 2.2 0.024
Q14624 14 Inter-alpha-trypsin inhibitor heavy chain H4 ITIH4 566.84 2.1 0.007
A0A3B3ISR2 30 Complement subcomponent C1r C1R 366.02 2 0.036
P02656 1 Apolipoprotein C-III APOC3 971.08 1.7 0.034
Q02413 2 Desmoglein-1 DSG1 340.05 1.6 0.017
P02743 7 Serum amyloid P-component APCS 1525.76 0.6 0.02
P02748 17 Complement component C9 C9 712.30 0.59 0.04
P02647 3 Apolipoprotein A-I APOA1 672.27 0.5 0.027
A0A0C4DGB6 5 Albumin ALB 191.37 0.48 0.007
Q5T985 24 Inter-alpha-trypsin inhibitor heavy chain H2 ITIH2 620.93 0.44 0.04
P06727 6 Apolipoprotein A-IV APOA4 566.64 0.4 0.01
Q5T985 25 Inter-alpha-trypsin inhibitor heavy chain H2 ITIH2 691.01 0.38 0.005
B1AKG0 13 Complement factor H-related protein 1 CFHR1 252.88 0.38 0.012
Q5T985 23 Inter-alpha-trypsin inhibitor heavy chain H2 ITIH2 792.30 0.32 0.04
P60709 11 Actin, cytoplasmic 1 ACTB 447.69 0.3 0.01

* Fold change was defined as the mean % volume ratio according to the formula: %V = Volume single spot/Volume total spot of EC vs. C.