Table 2.
Comparison between group with and without TCMR.
| No TCMR = 56 (68) | TCMR = 26 (32) | p-Value | |
|---|---|---|---|
| Pre LT data | |||
| Cholestatic disease | 37 (66) | 17 (65) | 1.0 |
| Age at LT (months) | 30 [10,115] | 18 [11,51] | 0.74 |
| Pre LT weight Z-score | −0.93 [−1.8,0.06] | −1.03[−2.13,0.05] | 0.6 |
| Pre LT height Z-score | −0.53[−1.53,0.7] | −0.23 [−1.2,0.6] | 0.66 |
| Nutritional support | 31 (55) | 15 (58) | 1.0 |
| PELD | 7 [–4,18] | 11[5,24] | 0.1 |
| MELD | 14 [10,24] | 18 [10,24] | 0.37 |
| Metabolism D vitamin | |||
| 25(OH)-D insufficiency * | 30 (53) | 22 (85) | 0.01 |
| Elevated plasma PTH * | 13 (23) | 9 (35) | 0.28 |
| Vitamin D supplementation | 46 (82) | 23 (88) | 0.53 |
| Nutritional support | 31 (55) | 15 (58) | 1.0 |
| CKD GFR < 60 (mL/min) | 10 (17) | 1 (4) | 0.16 |
| Immediate post LT data | |||
| Intubation time | 1.5 [1,5] | 3 [1,5] | 0.6 |
| Days hospitalization | 34 [26,44] | 39 [30,77] | 0.1 |
| Immune suppression post LT | |||
| With steroids | 41 (73) | 14 (53) | 0.13 |
| Tacrolimus > 8 ng/mL at 3 months | 34 (60) | 19 (73) | 0.3 |
| Complications post LT ** | |||
| CMV PCR positive | 13 (23) | 3 (11) | 0.25 |
| EBV PCR positive | 16 (29) | 2 (8) | 0.08 |
The data are presented as the number (percentage) or median [interquartile range], as appropriate. Total number of patients within each group is the reference to calculate the percentage. (No TCMR /56; TCMR /26). N = number. TCMR: T-cell mediated rejection. Pre LT/post LT: pre/post liver transplantation. 25(OH)D: 25 (OH) vitamin D. PTH: plasma parathyroid hormone. CKD: chronic kidney disease. * 25(OH)-D and PTH missing for 2 patients: N=80. ** For TCMR group, positive PCR were considered if performed before rejection.