Table 2.
Distributions of family cancer history and lung disease history by status of cases and controls, the corresponding ORs and 95% CIs among non-smokers
| Levels of exposure | Cases | Controls | p | OR and 95% CI* |
|---|---|---|---|---|
| N (%) (n = 767) | N(%) (n = 767) | |||
| Family cancer history | ||||
| Overall cancers | 162 (21.1%) | 169 (22.0%) | 0.185 | 1.189 (0.921, 1.535) |
| Type | < 0.001 | |||
| Lung cancer | 20 (2.6%) | 54 (7.0%) | < 0.001 | 3.347 (1.930, 5.806) |
| Other cancers | 142 (18.5%) | 115 (15.0%) | 0.509 | 0.909 (0.685, 1.206) |
| Relationship | 0.148 | |||
| First-degree relatives | 133 (17.3%) | 147 (19.2%) | 0.054 | 1.283 (0.995, 1.654) |
| Other relatives | 29 (3.8%) | 22 (2.9%) | 0.880 | 0.958 (0.550, 1.669) |
| Type of cancer and relatives | 0.002 | |||
| Lung cancer in father, mother or children | 13 (1.7%) | 28 (3.7%) | 0.006 | 2.646 (1.323, 5.291) |
| Lung cancer in siblings | 4 (0.5%) | 20 (2.6%) | 0.001 | 6.329 (2.058, 19.467) |
| Other cancers in father, mother or children | 81 (10.6%) | 73 (9.5%) | 0.767 | 0.948 (0.668, 1.347) |
| Other cancers in siblings | 35 (4.6%) | 26 (3.4%) | 0.558 | 0.850 (0.494, 1.463) |
| Lung cancer in other relatives | 3 (0.4%) | 6 (0.8%) | 0.166 | 2.804 (0.651, 12.0738) |
| Other cancers in other relatives | 26 (3.4%) | 16 (2.1%) | 0.538 | 0.812 (0.417, 1.578) |
| Lung disease history | ||||
| Overall lung disease | 44 (5.7%) | 73 (9.5%) | 0.001 | 2.041 (1.356, 3.071) |
| Type | 0.018 | |||
| Chronic bronchitis | 19 (2.5%) | 23 (3.0%) | 0.203 | 1.523 (0.797, 2.908) |
| Tuberculosis | 10 (1.3%) | 16 (2.1%) | 0.056 | 2.256 (0.980, 5.194) |
| Pneumonia | 8 (1.0%) | 15 (2.0%) | 0.127 | 2.014 (0.820, 4.946) |
| Asthma | 1 (0.8%) | 13 (1.7%) | 0.010 | 14.720 (1.877, 115.449) |
| Other | 6 (0.1%) | 6 (0.8%) | 0.785 | 1.177 (0.365, 3.793) |
The bold values represent P values less than 0.05
OR odds ratio, CI confidence interval
*Adjusted for sex, age, marriage, education, and occupation