Table 4.
ORs and 95% CIs according to combined effect of lung disease history, family lung cancer history and environmental exposure index score among non-smokers
| Risk factors | Without family lung cancer history | With family lung cancer history | ||||||
|---|---|---|---|---|---|---|---|---|
| Without lung disease history | With lung disease history | Without lung disease history | With lung disease history | |||||
| Cs/cnt | OR (95%CI) | Cs/cnt | OR (95%CI) | Cs/cnt | OR (95%CI) | Cs/cnt | OR (95%CI) | |
| EEI-1 | ||||||||
| Low | 101/345 | 1.000 | 11/24 | 1.493 (0.694, 3.213) | 7/9 | 3.597 (1.265, 10.226) | 0/2 | – |
| Intermediate | 227/247 | 2.784 (2.072, 3.741) | 21/10 | 7.565 (3.367, 16.998) | 12/6 | 7.975 (2.829, 22.486) | 1/0 | – |
| High | 314/113 | 8.163 (5.933, 11.231) | 40/8 | 17.584 (7.842, 39.427) | 33/3 | 35.143 (10.413, 118.602) | 0/0 | – |
| p value (test for trend) | < 0.001 | |||||||
| EEI-2 | ||||||||
| Low | 101/345 | 1.000 | 11/24 | 1.493 (0.694, 3.213) | 7/9 | 3.597 (1.265, 10.226) | 0/2 | – |
| Intermediate | 227/247 | 2.784 (2.072, 3.741 | 21/10 | 7.565 (3.367, 16.998) | 12/6 | 7.975 (2.829, 22.486) | 1/0 | – |
| High | 314/113 | 8.163 (5.933, 11.231) | 40/8 | 17.584 (7.842, 39.427) | 33/3 | 35.143 (10.413, 118.602) | 0/0 | – |
| p value (test for trend) | < 0.001 | |||||||
The bold values represent P values less than 0.05
ORs were adjusted for sex, age, marriage, education, occupation
Cs/cnt Case/Control, OR odds ratio, CI confidence interval
#The indicated subgroups were categorized by the tertiles of environmental exposure index (EEI) in the cases and controls