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. 2021 Jul 23;22:210. doi: 10.1186/s12931-021-01802-z

Table 5.

ORs and 95% CIs according to combined effect of lung disease history, family cancer history and environmental exposure index score among non-smokers

Risk factors# Without family cancer history With family cancer history
Without lung disease history With lung disease history Without lung disease history With lung disease history
Cs/cnt OR (95%CI) Cs/cnt OR (95%CI) Cs/cnt OR (95%CI) Cs/cnt OR (95%CI)
EEI-1
Low 89/278 1.000 7/19 1.178 (0.469, 2.959) 19/76 0.960 (0.543, 1.699) 4/7 1.788 (0.497, 6.434)
Intermediate 198/209 2.715 (1.977, 3.729) 17/7 7.960 (3.111, 20.367) 41/44 2.792 (1.684, 4.628) 5/3 5.916 (1.336, 26.199)
High 253/87 7.881 (5.547, 11.198) 34/5 22.306 (8.335, 59.700) 94/29 9.797 (5.990, 16.023) 6/3 6.729 (1.577, 28.718)
p value (test for trend)  < 0.001
EEI-2
Low 89/278 1.000 7/19 1.178 (0.469, 2.959) 19/76 0.960 (0.543, 1.699) 4/7 1.788 (0.497, 6.434)
Intermediate 198/209 2.715 (1.977, 3.729) 17/7 7.960 (3.111, 20.367) 41/44 2.792 (1.684, 4.628) 5/3 5.916 (1.336, 26.199)
High 253/87 7.881 (5.547, 11.198) 34/5 22.306 (8.335, 59.700) 94/29 9.797 (5.990, 16.023) 6/3 6.729 (1.577, 28.718)
p value (test for trend)  < 0.001

The bold values represent P values less than 0.05

ORs were adjusted for sex, age, marriage, education, occupation

Cs/cnt Case/ControlOR odds ratio, CI confidence interval

#The indicated subgroups were categorized by the tertiles of environmental exposure index (EEI) in the cases and controls