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. 2021 Jul 15;13(14):3548. doi: 10.3390/cancers13143548

Figure 6.

Figure 6

Protein, DNA, and phospholipid adducts are generated by the reaction of electrophilic acetaldehyde with nucleophilic groups. Additional secondary transformations may occur. dG, deoxyguanosine; GG, two contiguous deoxyguanosine on a DNA strand; MDA, malondialdehyde; MAA, malondialdehyde acetaldehyde; PE, phosphatidylethanolamine. The figure includes colored representations of a human nucleosome (Protein Data Bank, code 3AFA). DNA figure: doi.org/10.5281/zenodo.4012404 (accessed on 14 July 2021) [26,62,80,82,83,85,149,229,231].