14-3-3-BD |
14-3-3– binding domain |
AH |
Ack homology |
CRE |
cAMP response element |
CRIB |
Cdc42/Rac-interactive binding |
DEAD |
Asp-Glu-Ala-Asp box |
DDR |
DNA damage response |
EBD/EBR |
ErbB binding domain/region |
EMT |
epithelial mesenchymal transition |
GR |
glucocorticoid receptor |
GRE |
glucocorticoid response element |
HRE |
HIF-response element |
LOH |
loss of heterozygosity |
LPA |
lysophosphatidic acid |
Mig6 |
mitogen-inducible gene 6 |
NLS |
nuclear localization signal |
PDGF |
platelet-derived growth factor |
PDZ-BD |
PDZ binding domain |
PEST |
Pro, Glu, Ser, Thr-rich sequence |
RALT |
receptor-associated late transducer |
RED |
RALT endocytic domain |
RTK |
receptor tyrosine kinase |
SH2 |
Src homology 2 |
SH3-BD |
Src homology 3 binding domain |
SNP |
single nucleotide polymorphism |
SRE |
serum response element |
TCGA |
the cancer genome atlas |
TKI |
tyrosine kinase inhibitor |
TNBC |
triple negative breast cancer |
TRE |
TPA response element |
BRafV600E |
valine to glutamate mutation at amino acid 600 of BRAF |