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. 2021 Jul 9;13(14):3445. doi: 10.3390/cancers13143445
Abbreviation Definition
AL (A-loop) Activation loop
CCAR1 Cycle and apoptosis regulator 1
CDK Cyclin-dependent kinase
CKI Cyclin-dependent kinase inhibitor
DNA-PK DNA-dependent protein kinase
EGFR Epidermal growth factor receptor
EMT Epithelial-to-mesenchymal transition
ER Estrogen receptor
ErbB2 Epidermal growth factor receptor 2
ERK Extracellular signal-regulated kinase
FADD Fas-associated death domain
HER2 Human epidermal growth factor receptor 2
HM Hydrophobic motif
MAP1LC3/LC3 Microtubule-associated protein 1 light chain 3
MEF Mouse embryo fibroblasts
mTOR Mechanistic target of rapamycin
mTORC1 Mechanistic target of rapamycin complex 1
mTORC2 Mechanistic target of rapamycin complex 2
NF1 Neurofibromin 1
PDK1 Phosphoinositide-dependent kinase 1
PH Pleckstrin homology
PHLPP PH domain and leucine-rich repeat protein phosphatase
PI3K Phosphatidylinositol 3- kinase
PIK3CA PI3K catalytic subunit alpha
PIP2 Phosphatidylinositol (4,5)-bisphosphate
PIP3 Phosphatidylinositol (3,4,5)-triphosphate
PKB Protein kinase B
PP2A Protein phosphatase 2A
PR Progesterone receptor
PKC Protein kinase C
PTEN Phosphatase and tensin homolog deleted on chromosome 10
SETDB1 SET domain bifurcated 1
Skp2 S-phase kinase associated protein 2
TCGA The cancer genome atlas
TERT Telomerase reverse transcriptase
TFEB Transcription factor EB
TIM TOR-interacting motif
TM Turn motif
TNBC Triple-negative breast cancer
TRAF6 Tumor necrosis factor receptor-associated factor 6
UVRAG Ultraviolet irradiation resistance-associated gene