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DCN activates AKT signaling in murine ON astrocytes. pAKT/AKT ratio was significantly higher in murine ON astrocytes treated with 25 nM of DCN for 6 h (1.47 ± 0.09, n = 3, p ≤ 0.01) in comparison to untreated controls (1.04 ± 0.09, n = 3) speaking for an activation of the pAKT/AKT signaling pathway in this cell type. pAKT and AKT were normalized to α-Tubulin. ** are significant with p ≤ 0.01.
