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. 2021 Jun 23;11(7):1652. doi: 10.3390/nano11071652

Table 1.

Comparison between selected magnetic nanoparticle manufacturing methods.

Manufacturing Method Synthesis Reaction Temp. (°C) Reaction Time Solvent Surface-Capping Agents Size Distribution Shape Control Yield
Coprecipitation Very simple 20–90 Minutes Water During/after reaction Relatively narrow Not good High
Microemulsion Complicated 20–50 Hours Organic agents During reaction Relatively narrow Good Low
Thermal decomposition Complicated 100–320 Hours-days Organic agents During reaction Very narrow Very good High
Hydrothermal Simple 200–250 Hours-days Water-ethanol During reaction Very narrow Very good Medium
Poliol Simple 25-Boiling Point Hours Ethylene PEG During reaction Narrow Very Good High