Table 5.
Changes in liver damage and inflammation indices.
| AGM Group (n = 37) | Placebo Group (n = 39) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 12-Week | Change Value | p Value (2) | Baseline | 12-Week | Change Value | p Value (2) | p Value (3) | |
| γ-GT (U/L) | 28.8 ± 24.7 (1) | 23.9 ± 16.4 | −4.90 ± 12.4 | 0.022 * | 33.6 ± 24.7 | 34.4 ± 25.7 | 0.83 ± 14.4 | 0.721 | 0.068 |
| AST (U/L) | 26.6 ± 9.0 | 21.8 ± 5.2 | −4.77 ± 8.96 | 0.003 ** | 24.9 ± 6.6 | 24.3 ± 8.0 | −0.58 ± 6.12 | 0.556 | 0.021 * |
| ALT (U/L) | 27.1 ± 13.8 | 20.6 ± 10.0 | −6.48 ± 10.7 | 0.001 ** | 28.9 ± 15.6 | 29.4 ± 18.1 | 0.52 ± 14.6 | 0.824 | 0.020 * |
| hs-CRP (mg/L) | 0.87 ± 0.78 | 0.72 ± 0.64 | −0.15 ± 0.84 | 0.299 | 0.85 ± 0.99 | 1.34 ± 2.02 | 0.50 ± 1.98 | 0.126 | 0.069 |
(1) Values are presented as mean ± SD. (2) Analyzed by paired t-test between baseline and 12 weeks within the group. (3) Analyzed by independent t-test for the changed values from baseline to 12-week between the AGM and placebo groups between groups. * p < 0.05, ** p < 0.01. AGM, Mixture of Aronia, red ginseng, Shiitake mushroom, and nattokinase.