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. 2021 Jul 23;21:853. doi: 10.1186/s12885-021-08605-x

Table 2.

Indirect comparison of overall survival

HR of OS (95% CI)
GEM
 2.03 (1.63–2.54) * GEM-NAB
 2.19 (1.77–2.71) * 1.08 (0.92–1.25) FOLFIRINOX
 2.29 (1.55–3.40) * 1.13 (0.78–1.63) 1.05 (0.75–1.47) mFOLFIRINOX

Abbreviation: HR: hazard ratio; OS: overall survival; CI: confidence interval; GEM: gemcitabine; GEM-NAB: Gemcitabine plus nab-paclitaxel; FOLFIRINOX: the combination of 5-fluorouracil, oxaliplatin, and irinotecan; mFOLFIRINOX: at least one of the drugs was reduced and/or the removal of 5-FU bolus in FOLFIRINOX

Notes: Comparisons between treatments were read from left to right, and the estimate (HR) with 95% CI for a given comparison was read in the intersection of two treatments. The value of estimates higher than 1 indicated that column-defining treatment had better efficacy

* Denotes p-value < 0.05