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. 2021 Jul 23;21:526. doi: 10.1186/s12884-021-04006-x

Table 1.

General characteristics comparison

Non-IR GDM IR GDM Test Statistic P
Number 418 292
Age (years) 33.20 ± 4.127 32.72 ± 4.255 1.495 0.135
Parity 1.014 0.314
 Primiparity 239(57.3%) 178(42.7%)
 Multiparity 179(61.1%) 114(38.9%)
Glycemic control 6.441 0.040
 Good 412(59.5%) 280(40.5%)
 Poor 6(33.3%) 12(66.7%)
IVF-ET 0.268 0.604
 Yes 48(61.5%) 30(38.5%)
 No 370(58.5%) 262(41.5%)
History of GDM 0.669 0.413
 Yes 10(50%) 10(50%)
 No 408(59.1%) 282(40.9%)
Family history of diabetes 2.190 0.139
 Yes 98(54.1%) 83(45.9%)
 No 320(60.5%) 209(39.5)
Pre-pregnant BMI category 97.157  < 0.001
 Underweight (less than18.5) 51(89.5%) 6(10.5%)
 Normal (18.5 to 23.9) 307(66.6%) 154(33.4%)
 Overweight (24.0 to 27.9) 50(35.2%) 92(64.8%)
 Obesity (28 or more) 10(20%) 40(80%)
FPG (mmol/L) 4.70 ± 0.44 4.85 ± 0.49 -4.145  < 0.001
HbA1c (%) 5.26 ± 0.28 5.38 ± 0.30 -5.684  < 0.001
HOMA-β 85.64(68.94,110.67) 141.36(114.13,182.18) 18,787.000  < 0.001
Serum Lipid
TC (mmol/L) 4.35 ± 0.83 4.55 ± 0.93 -2.985 0.003
TG (mmol/L) 1.23 ± 0.92 1.59 ± 1.46 -3.792  < 0.001
Serum protein
TP (mmol/L) 73.0 ± 4.13 73.57 ± 3.90 -1.873 0.061
ALB (mmol/L) 42.53 ± 3.15 42.48 ± 2.83 0.209 0.835
Weight gain before diagnosis of GDM (kg) 5.24 ± 3.00 5.36 ± 3.27 -0.506 0.613
GWG (kg) 10.65 ± 4.57 10.96 ± 5.40 -0.893 0.402
Excessive GWG 32.949  < 0.001
 Yes 41(35%) 76(65%)
 No 377(63.6%) 216(36.4%)
aGWG (kg) 10.77 ± 4.53 10.96 ± 5.34 -0.47 0.638
aBirth weight (g) 3343.60 ± 390.24 3423.77 ± 434.55 -2.461 0.014

a Non-IR GDM group (n 404), IR GDM group (n 276), with 30 cases of preterm birth excluded; IVF-ET In vitro fertilisation-embryo transfer; Test Statistic: P-values were estimated from the resulting t-values for normally distributed data, and were estimated from the resulting U-values for non-normally distributed data, and were estimated from the resulting χ2-values for counting data