n.c.a. |
No carrier added |
PET |
positron emission tomography |
THF |
tetrahydrofuran |
HPLC |
high-performance liquid chromatography |
RCY |
radiochemical yield |
BBB |
blood–brain barrier |
d.c. |
Decay-corrected |
RCP |
radiochemical purity |
DMSO |
dimethyl sulfoxide |
WT |
wild type |
CT |
computed tomography |
TLC |
Thin-layer chromatography |
SPECT |
single-photon-emission computed tomography |
AD |
Alzheimer’s disease |
PSMA |
Prostate-specific membrane antigen |
DOTA |
1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid |
NODAGA |
1,4,7-triazacyclononane,1-glutaric acid-4,7-acetic acid |
AAZTA |
1,4-bis(carboxymethyl)-6-[bis(carboxymethyl)]amino-6-methylperhydro-1,4-diazepine |
DMF |
dimethylformamide |
DIPEA |
N,N-diisopropylethylamine |
TFA |
trifluoroacetic acid |
DCM |
dichloromethane |
HBTU |
(2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate |
TIS |
triisopropyilsilane |
tBuHPC |
tert-butyl bromopropylamine carbamate |
PBS |
phosphate-buffered saline |
HS |
human serum |
HB |
human blood |