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. 2021 Jun 29;10(7):1625. doi: 10.3390/cells10071625

Figure 7.

Figure 7

Alterations in expression of membrane transport-associated proteins with age. Histograms of TOM20, TIM23, and GRIM19 fluorescent mean grayscale value/cell (MGV/cell): (A–C) comparison of young (2- and 6-months old) and older (12- and 18-months old) neurons, as well as (A–C) between 2-, 6-, 12- and 18-month=old neurons; (A,Ai) show an age-related trend for a decrease in TOM20 expression per cell, though these were not significant; (B,Bi) show significant increases in the TIM23 expression with age; (C,Ci) show decreases in GRIM19 MGV per cell. * (p < 0.05), ** (p < 0.005), **** (p < 0.0001). N = 50–75 cells/age. Graphs show mean and SEM.