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Dose response curves of peripheral blood mononuclear cells from four donors (C162-165) treated with the clinically tested S. sonnei GMMA drug product (DP, 1790GAHB SH15-001, black circles), S. sonnei GMMA DP (1790GAHB FF01, pink squares) or three independent GMMA DP batches (A: Green triangles, B: Dark purple inverted triangles, C: Light purple diamonds). The highest concentration of S. sonnei GMMA DPs was 12.5 ng/mL for donors C162, 164 and 165, and 3.125 ng/mL for donor C163.
