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. 2021 Jul 18;10(7):1816. doi: 10.3390/cells10071816

Figure 2.

Figure 2

IL-6 overexpression significantly impairs muscle growth during the postnatal life. (a,b) Hematoxylin and eosin staining of transverse section of soleus muscles from indicated genotypes at 1.5 and 3.5. Scale bar 500μm. (c–e) The graphs show quantification of total cross-sectional area (muscle CSA) (c), fibers-cross sectional area (Fiber CSA) (d) and total number of fibers (e) in soleus muscles of wild type (WT) and NSE/IL-6 (IL-6) mice at 1.5 and 3.5 months of age. Data are represented as average ± SEM. n = 10 mice; ** p < 0.01, **** p < 0.0001. Statistical significance assessed by two-way ANOVA.