Table 2.
Measured values of nicotinamide mole fraction (103) in saturated solution of neat solvents. Ideal solubility was estimated using Equation (1) and DSC data provided herein.
| T (K) | 298.15 | 303.15 | 308.15 | 313.15 |
|---|---|---|---|---|
| water | 99.9 ± 5.1 | 114.9 ± 4.6 | 133.2 ± 2.4 | 154.2 ± 4.2 |
| 1,4-dioxane | 16.9 ± 0.9 | 20.4 ± 0.8 | 24.6 ± 0.7 | 30.4 ± 0.6 |
| DMSO | 120.6 ± 3.5 | 150.7 ± 7.1 | 198.7 ± 3.2 | 265.5 ± 3.8 |
| DMF | 206.1 ± 11.9 | 226.7 ± 11.1 | 271.8 ± 9.3 | 325.9 ± 3.5 |
| acetonitrile | 8.6 ± 0.5 | 10.9 ± 0.5 | 13.4 ± 0.4 | 16.0 ± 0.2 |
| methanol | 74.1 ± 3.5 | 85.6 ± 2.5 | 100.1 ± 4.4 | 115.7 ± 2.6 |
| ideal | 118.12 | 133.08 | 149.60 | 167.82 |