Table 3.

Diagnostic performance of each reader for both mpMRI and bpMRI.

bpMRI
	Detection of PCa (Any GS)						Detection of High-Grade PCa (GS > 7)
	Reader 1			Reader 2			Reader 1			Reader 2
		95 % CI			95 % CI			95 % CI			95 % CI
Sens	0.84	0.79	0.89	0.80	0.74	0.86	0.84	0.75	0.93	0.80	0.70	0.90
Spec	0.77	0.72	0.82	0.74	0.68	0.80	0.77	0.73	0.81	0.74	0.70	0.78
PPV	0.75	0.69	0.81	0.72	0.66	0.78	0.39	0.31	0.47	0.35	0.28	0.43
NPV	0.85	0.81	0.90	0.82	0.77	0.87	0.96	0.94	0.99	0.95	0.93	0.98
1-NPV	0.15	0.10	0.19	0.18	0.13	0.23	0.04	0.01	0.06	0.05	0.02	0.07
LR+	3.65	2.87	4.65	3.08	2.45	3.86	3.65	2.94	4.53	3.08	2.49	3.80
LR−	0.21	0.15	3.82	0.27	0.20	3.21	0.21	0.12	1.71	0.27	0.17	1.52
DOR	17.58	10.79	28.64	11.38	7.22	17.96	17.58	8.67	35.62	11.38	5.94	21.83
Accuracy	0.80			0.77			0.78			0.75
mpMRI
	Detection of PCa (Any GS)						Detection of High-Grade PCa (GS > 7)
	Reader 1			Reader 2			Reader 1			Reader 2
		95 % CI			95 % CI			95 % CI			95 % CI
Sens	0.86	0.81	0.91	0.82	0.77	0.87	0.86	0.78	0.94	0.80	0.70	0.90
Spec	0.78	0.73	0.83	0.75	0.69	0.81	0.78	0.74	0.82	0.74	0.70	0.78
PPV	0.76	0.71	0.82	0.73	0.67	0.79	0.41	0.33	0.49	0.35	0.28	0.43
NPV	0.87	0.83	0.92	0.83	0.78	0.88	0.97	0.95	0.99	0.95	0.93	0.98
1-NPV	0.13	0.08	0.17	0.17	0.12	0.22	0.03	0.01	0.05	0.05	0.02	0.07
LR+	3.91	3.05	5.00	3.28	2.60	4.13	3.91	3.15	4.85	3.08	2.49	3.80
LR−	0.18	0.13	4.10	0.24	0.18	3.43	0.18	0.10	1.81	0.27	0.17	1.52
DOR	21.78	13.10	36.21	13.67	8.55	21.85	21.78	10.36	45.78	11.38	5.94	21.83
Accuracy	0.82			0.78			0.79			0.76

PCa: Prostate Cancer, GS: Gleason Score, Sens: sensitivity, Spec: specificity, PPV: positive predictive value, NPV: negative predictive value, LR: likelihood ratio, and DOR: diagnostic odds ratio.