Figure 1.

Venn diagram of the interactors in the manually curated core map vs. coarse map. The manually curated list of interactors within the core map comprises 170 interactors, the coarse map derived from high-throughput data contains 1384 interactors, and 46 interactors occur in both lists. The overlap was subtracted from the high-throughput interactome for the visualization to avoid redundancies, resulting in 1338 interactors in the coarse map.