Table 1.

Description of the five submaps of the CFTR core map.

Process	Localization	Molecular Entities Present in the Model	N 1	Proportion of the Interactors Identified in Polarized Cells
Transcription	Nucleus	Proteins	28	97%
		RNAs and gene elements	16
		Small molecules and ions	1
Translation, Folding and ER quality control	ER	Proteins	45	69%
		Small molecules and ions	13
Secretory pathway	ER, Golgi apparatus, Plasma Membrane	Proteins	27	52%
		Small molecules and ions	8
Activity and Regulation	Plasma Membrane	Proteins	44	82%
		Small molecules and ions	20
Endocytosis, Recycling and Degradation	Plasma Membrane, Endosomes, Lysosomes	Proteins	23	74%

¹ Number of different molecular entities present in the respective submap.