Table 3.
Haplotype distributions and the severity of LCPD hips based on Catterall classification.
| Haplotypes | ||||
|---|---|---|---|---|
| Low Risk * | Intermediate Risk * | High Risk * | p | |
| Catterall I | 1 (3.2%) | 1 (7.1%) | 1 (16.7%) | 0.05 |
| Catterall II | 2 (6.5%) | 5 (35.7%) | 0 | |
| Catterall III | 16 (51.6%) | 4 (28.6%) | 1 (16.7%) | |
| Catterall IV | 12 (38.7%) | 4 (28.6%) | 4 (66.6%) | |
* Low-risk haplotypes: a combination of normal homozygous status for the PlA2 (A1A1) polymorphism with normal homozygous (CC) and heterozygous (CT) status for the C677T mutation of MTHFR. Intermediate-risk haplotypes: heterozygous for the PlA2 (A1A2) polymorphism plus normal homozygous (CC) or heterozygous (CT) for the C677T mutation of the MTHFR gene. High-risk haplotypes: a combination of homozygous MTHFR (TT) or PlA2 (A2A2).