αSMA	alpha smooth muscle actin
ABC	ATP-binding cassette
apCAF	Antigen-presenting CAF
Arg2	Arginase 2
CAR	Chimeric antigen receptor
CAF	Cancer-associated fibroblast
CD10	Cluster of differentiation 10
CSCs	Cancer stem cells
ECM	Extracellular matrix
CXCL1	C-X-C Motif Chemokine Ligand 1
CXCL12	C-X-C Motif Chemokine Ligand 12
EGF	Epidermal growth factor
EGFR	Epidermal growth factor receptor
ELR	Glu-Leu-Arg motif
EMT	Epithelial-to-mesenchymal transition
ERK	Extracellular signal-regulated kinase
EVs	Extracellular vesicles
FAK	Focal adhesion kinase
FAPα	Fibroblast-activation protein alpha
FGF	Fibroblast growth factor
FGF2	Fibroblast growth factor 2
FSP-1	Fibroblast-specific protein 1
GLI2	GLI Family Zinc Finger 2
GPR77	G-protein coupled receptor 77
HAS1	Hyaluronan synthase 1
HAS2	Hyaluronan synthase 2
HER2	Human epidermal growth factor receptor 2
HGF	Hepatocyte growth factor
HIF1α	Hypoxia-inducible factor 1-alpha
HLA	Human leukocyte antigen
iCAF	Inflammatory CAF
ICD	Immunogenic cell death
IDO1	Indoleamine 2,3-Dioxygenase 1
IFNβ1	Interferon-beta 1
IGF1	Insulin-like growth factor
IGF1R	Insulin-like growth receptor-1
IL-1	Interleukin 1
IL-6	Interleukin 6
IL-15	Interleukin 15
ILs	Interleukins
IRDS	Interferon-related DNA damage resistance signature
IRF3	Interferon-regulatory factor 3
ISGs	Interferon-stimulated genes
KRAS	Kirsten rat sarcoma viral oncogene homolog
MAPK	Mitogen-activated protein kinase
MDSC	Myeloid-derived suppressor cell
MHC	Major histocompatibility complex
miRNAs	microRNAs
MMPs	Matrix metalloproteinases
myCAF	Myofibroblast CAF
NF-κB	Nuclear factor-κB
NK	Natural killer
NRG1	Neuregulin 1
PD1	Programmed cell death protein 1
PDAC	Pancreatic ductal adenocarcinoma
PDGF	Platelet-derived growth factor
PGE2	Prostaglandin E2
PI3K	Phosphoinositide 3-kinase
RIG-I	Retinoic acid-inducible gene I
RNA	Ribonucleic acid
ROS	Reactive oxygen species
SASP	Senescence-associated secretory phenotype
Shh	Sonic Hedgehog
STAT1	Signal transducer and activator of transcription 1
STING	Stimulator of interferon genes
T reg	Regulatory T cell
TGF-β	Transforming growth factor beta
TME	Tumour microenvironment
TKI	Tyrosine kinase inhibitor
TSP1	Thrombospondin 1
VEGF	Vascular endothelial growth factor
YAP	Yes-associated protein