Table 2.
pMHCI/CD8 dissociation constants for variants of HLA-A2
| MHCI | Mutation | KD (μM) |
| HLA-A2 D227K/T228A | MHCI α3 domain | >10,000 |
| HLA-A2 WT | N/A | 137 ± 9.7 |
| HLA-A2 A245V/Kb | MHCI α3 domain | 27 ± 1 |
| HLA-A2 Kb | MHCI α3 domain | 11 |
N/A, not applicable.
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