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. 2021 Jun 24;10(7):1591. doi: 10.3390/cells10071591

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Unrooted tree of selected HhH DNA glycosylases. The species are: Afu, Archaeoglobus fulgidus; Ath, Arabidopsis thaliana; Bha, Alkalihalobacillus (formerly Bacillus) halodurans; Bst, Geobacillus (formerly Bacillus) stearothermophilus; Cac, Clostridium acetobutylicum; Cel, Caernorhabditis elegans; Csu, Caldanaerobacter subterraneus (formerly Thermoanaerobacter tengcongensis); Dme, Drosophila melanogaster; Dra, Deinococcus radiodurans; Eco, Escherichia coli; Hpy, Helicobacter pylori; Hsa, Homo sapiens; Mja, Methanocaldococcus jannaschii; Mlu, Micrococcus luteus; Mth, Methanothermobacter thermautotrophicus (formerly Methanobacterium thermoformicicum); Sce, Saccaromyces cerevisiae; Spo, Schizosaccharomyces pombe; Sso, Saccharolobus (Sulfolobus) solfataricus; Tma, Thermotoga maritima. The selected proteins are HhH DNA glycosylases characterized either biochemically or structurally. The phylogenetic tree was produced by Clustal Omega [124] and visualized using iTOL [125].