Depressed humor: sadness, hopelessness, discouragement, “feeling low”
Lack of interest or pleasure in activities that were previously enjoyed
Changes in appetite, with significant weight loss or weight gain
Insomnia or hypersomnia
Psychomotor changes marked by agitation or slowness
Fatigue or loss of energy
Feelings of guilt or personal devaluation, frequently regarding daily situations
Reduced ability to concentrate, think, and make decisions
Death thoughts: suicidal ideation
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