Table 4.
Correlation between HLA-I, HLA-II, PD-L1 expression and T-cell infiltration patterns.
| Infiltration Pattern | Total | p-Value * | ||
|---|---|---|---|---|
| TILs | Stromal | |||
| HLA-I expression | ||||
| Positive | 60 (85%) | 11 (15%) | 71 (56%) | 6.44 × 10−10 |
| Total/Partial loss | 18 (31%) | 40 (69%) | 58 (44%) | |
| HLA-II expression | ||||
| Positive | 14 (82%) | 3 (18%) | 17 (13%) | 0.048 |
| Negative | 64 (57%) | 48 (43%) | 112 (87%) | |
| PD-LI expression | ||||
| Positive/het | 30 (79%) | 8 (21%) | 38 (51%) | 1.8 × 10−5 |
| Negative | 11 (31%) | 26 (70%) | 37 (48%) | |
* The results were obtained performing chi-square test with IBM SPSS Statistics Ver.21.0 software. Differences between different groups were considered statistically significant at p < 0.05.