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. 2021 Jul 16;13(14):3556. doi: 10.3390/cancers13143556

Figure 2.

Figure 2

Precision medicine-mediated patient profiling for mCRPC management. Besides routine diagnostics, multiple screenings should be included in the diagnostic process. Genomic analysis for mutation status such as BRCA1/2, PTEN, AR and others should be combined with gene expression analysis and subsequent analysis of interactions and networks. 68Ga-PSMA-PET/CT is an indispensable component of this screening process and allows detection of tumor distribution and load. mCRPC: metastatic castration-resistant prostate cancer; BRCA1/2: breast cancer 1/2 gene; PTEN: phosphatase and tensin homolog on chromosome ten; AR: androgen receptor; 68Ga: 68Gallium; PSMA: prostate-specific membrane antigen; PET/CT: positron-emission tomography/computer tomography. This figure was generated using biorender, www.biorender.com, accessed on 8 July 2021.