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A higher BMP7-pSmad5 level in human malignant glioma. BMP7 and pSmad5 levels in malignant glioma, low-grade glioma, and normal brain tissue were analyzed by immunohistochemical stain with BMP7- and pSmad5-specific antibodies. The mean immunohistochemical stain scores of BMP7 and pSmad5 levels were shown in the right panel. Results are representative of three independent experiments with similar results. Scale bars are 20 μm. *, p = 0.001 vs. normal brain tissue.
