Table 4.

Evaluated adjustable parameters of Models V and VI used for SFE modeling.

	Model V					Model VI
Run	Y ∞	G	Km	t 1	ti	k f	k s	tc 1	tc 2
	(%)	(min−1)	(%)	(min)	(min)	(min−1)	(min−1)	(min)	(min)
Box-Behnken Experimental Design
1	3.88	0.493	228.16	329.67	3.88	0.050	0.026	194.46	204.81
2	3.79	0.900	130.01	500.00	3.79	0.030	0.029	127.88	217.03
3	3.31	0.800	136.72	500.01	3.31	0.044	0.020	180.00	205.76
4	2.64	0.800	144.81	421.97	2.64	0.016	0.025	182.89	295.91
5	2.82	0.800	147.48	388.93	2.81	0.025	0.010	118.63	321.91
6	3.91	0.800	136.44	365.38	3.91	0.019	0.024	107.56	348.93
7	3.88	0.777	215.38	349.89	3.88	0.026	0.004	192.19	209.36
8	3.88	0.409	233.92	339.62	3.88	0.028	0.019	179.36	373.64
9	4.75	0.800	81.34	477.01	4.75	0.023	0.008	200.00	493.26
10	5.59	0.800	188.83	329.53	5.59	0.023	0.016	184.45	489.20
11	4.17	0.800	152.21	291.10	4.17	0.017	0.011	197.54	464.52
12	3.88	0.710	203.19	322.60	3.88	0.019	0.013	130.21	282.01
13	3.89	0.800	155.88	306.12	3.89	0.021	0.022	161.25	334.66
14	3.88	0.785	155.59	306.08	3.88	0.040	0.026	164.86	249.71
15	5.91	0.800	94.72	787.47	5.91	0.047	0.030	92.51	499.689
Additional Experiments
16	5.80	0.800	70.92	446.78	5.80	0.041	0.010	195.64	334.39
17	5.71	0.782	79.28	617.99	5.71	0.040	0.028	188.37	477.63
18	3.94	0.800	76.88	361.10	3.94	0.022	0.026	128.44	417.75
19	3.88	0.632	226.28	346.98	3.88	0.028	0.019	44.56	411.69

G—parameter related to particle size and fragmentation; K_m—mass related coefficient; Y_∞—total yield in infinite time of extraction process (%); t₁—time constant extraction rate (min); t_i—time of internal mass transfer (min); k_f—solvent-phase mass transfer coefficient (min-1); k_s—solid-phase mass transfer coefficient (min⁻¹).