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. 2021 Jul 7;22(14):7289. doi: 10.3390/ijms22147289

Figure 4.

Figure 4

Localization of stress signaling components within ovarian follicles of several mammalian species. Nuclear glucocorticoid receptor NR3C1 has been detected throughout folliculogenesis in human, primate, and ovine models. GRs are also present throughout folliculogenesis in bovine and murine models, though only reported in oocytes in the latter. Enzymes HSD11B1 and HSD11B2 have been detected in human granulosa cells and bovine follicles throughout folliculogenesis.