Table 1.

Comparison of the tumor growth rate in young and aged mice.

Cell Lines	Young Group Age	Old Group Age	Mouse Strain	Number of Cells Injected	Injection Site	Tumor Growth in Old vs Young	References
B16/F10	2.5–6 months	19–26 months	C57/BL/6	500,000	Intradermal		Padrón et al., 2018 [58]
BSC9AJ2	8–10 weeks	10 months	C57BL/6	100,000	Intradermal		Kugel et al., 2018 [64]
4T1	8–10 weeks	>12 months	Balb/C	100,000	Mamarry fatpad		Sceneay et al., 2019 [91]
Met1			FVB	200,000
AE17	3 months	20–24 months	C57BL/6	500,000	Subcutaneous		Duong et al., 2018 [113]
TS/A	2 months	12 months	BXD12	150,000	Subcutaneous		Grizzle et al., 2007 [132]
B16/F10	2–6 months	22–26 months	C57BL/6	250,000	Subcutaneous		Hurez et al., 2012 [134]
MC38				1,000,000
B16/F10	3 months	24 months	C57BL/6	100,000	Subcutaneous		Ershler et al., 1984 [139]
B16/F1					Intravenous
B16/F10	4 months	20 months	C57BL/6	1,000,000	Subcutaneous		Reed et al., 2006 [140]
TRAMP-C2
MC38	3–4 months	12–15 months	C57BL/6	1,000,000	Subcutaneous		Oh et al., 2018 [142]
B16/F10
4T1			Balb/C
TRAMP-C2	4 months	20–24 months	C57BL/6	500,000	Dorsolateral prostate		Bianchi-Frias et al., 2019 [143]