Figure 3.

Validation of overexpression of eight exosomal protein markers in hepatocellular carcinoma (HCC) and its clinical relevance through TCGA_LIHC dataset. (a) TCGA_LIHC analysis in HCC tissues (n = 371) compared with that in non-tumor tissues (n = 50) (left), and expression of candidate genes according to tumor histologic grade (right). (Welch’s t-test; * p < 0.05, ** p < 0.01, *** p < 0.001) (b) Kaplan–Meier plot for overall survival according to mRNA expression of exosomal proteins in TCGA_LIHC. The p-value was obtained with the log-rank test.