Table 1.

Significantly (p ≤ 0.05) differentially expressed proteins in neovascular age-related macular degeneration (AMD) patients as identified by MALDI-TOF MS. Listed molecular weights and pI values correspond to the MASCOT search results; carbamidomethylation of cysteine was a global modification. Rt (Ratio) quotient of the group means of relative spot volumes; volume of a given spot in control group is the denominator of the ratio parameter.

ID	Protein	Accession Number (UniProtKB)	Species	Score	Match	MW (Da)	pI	Seq. Cov (%)	Rt	p-Value
1	ATP-dependent translocase ABCB1	P08183	H. sapiens	87	11	141,788	9.06	9	2.193	0.025
5	Annexin A1	P04083	H. sapiens	96	12	38,918	6.57	41	0.664	0.026
6	Annexin A1	P04083	H. sapiens	59	9	38,918	6.57	30	0.575	0.017
8	Aldo-keto reductase family 1 member A1	P14550	H. sapiens	146	15	36,892	6.32	48	0.638	0.029
10	Retinal dehydrogenase 1	P00352	H. sapiens	75	9	55,454	6.30	24	2.027	0.011
12	Uncharacterized protein C11orf98	E9PRG8	H. sapiens	76	5	14,225	11.53	38	0.560	0.008
15	Glutathione S-transferase P	P09211	H. sapiens	89	8	23,569	5.43	50	0.529	0.007
23	Retinal dehydrogenase 1	P00352	H. sapiens	121	14	55,454	6.30	41	1.991	0.015
24	Alpha-enolase	P06733	H. sapiens	67	11	47,481	7.01	29	1.476	0.022
11	Annexin A4	P09525	H. sapiens	94	14	36,088	5.84	14	0.393	0.003
21	Annexin A1	P04083	H. sapiens	76	11	38,918	6.57	35	0.213	0.008
31	Allograft inflammatory factor 1	P55008	H. sapiens	77	5	16,693	5.97	34	0.560	0.026
33	Cytospin-A or Elongation factor 2	Q69YQ0 P13639	H. sapiens	113 88	16 12	124,925 96,246	5.52 6.41	16 12	0.560	0.037
32	Short stature homeobox protein 2	O60902	H. sapiens	65	5	35,160	8.99	12	0.529	0.041

Abbreviations: MW—molecular weight; pI—isoelectric point; Seq. Cov—sequence coverage; Rt—ratio.