Table 1.
Patient demographics, antibiograms, sequence types, carbapenemase, other β-lactamases, and ARGs in K. pneumoniae isolates.
| Isolate | Demographic Information | Resistome | Plasmid Incompatibility Group | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Patient | Gender | Date | Study Day | Antibiogram | ERIC Type | Other β-Lactamases | Other ARGs | ||
| EC03607709 | P2 | Male | 19 February 2020 | Week 2 | A | 2 | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id, qnrS1, qnrB1, oqxB, oqxA, dfrA14, sul2, fosA, catB3, tet(A) | ColKP3, IncFIB(K), IncFII(K), IncX3 |
| EC03605938 | P13 | Male | 18 February 2020 | 48 h | B | 2 | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3′)-VIa, armA, qnrS1, oqxB, oqxA, dfrA14, fosA, msr(E), mph(E), catB3, tet(A), cmlA1, ARR-2 | ColKP3, IncFIB(K), IncFII(K), IncX3 |
| EC03607707 | P13 | Male | 19 February 2020 | 72 h | A | 1 | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3′)-VIa, armA, qnrS1, oqxB, oqxA, dfrA14, fosA, msr(E), mph(E), catB3, tet(A), cmlA1 | ColKP3, IncFIB(K), IncFII(K), IncX3 |
| EC03612985 | P22 | Female | 24 February 2020 | Discharge | C | 5 | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1C | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id, qnrS1, qnrB1, oqxB, oqxA, dfrA14, sul2, fosA, catB3, tet(A) | ColKP3, IncFIB(pNDM-Mar), IncX3 |
| EC03623002 | P30 | Male | 3 March 2020 | 48 h | A | 1 | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)- Id, qnrS1, qnrB1, oqxB, oqxA, dfrA14, sul2, fosA, catB3, tet(A) | ColKP3, IncFIB(K), IncFII(K), IncX3 |
| EC03629993 | P30 | Male | 8 March 2020 | Mero D4 | A | 2 | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id, qnrS1, qnrB1, oqxB, oqxA, dfrA14, sul2, fosA, catB3, tet(A) | ColKP3, IncFIB(K), IncFII(K), IncX3 |
| EC03632007 | P30 | Male | 10 March 2020 | Mero D6 | A | 4b | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id, qnrS1, qnrB1, oqxB, oqxA, dfrA14, sul2, fosA, catB3, tet(A) | ColKP3, IncFIB(K), IncFII(K) |
| EC03638959 | P30 | Male | 14 March 2020 | Week 2 | A | 4a | blaCTX-M-15, blaOXA-1, blaSHV-106, blaTEM-1B | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id, qnrS1, qnrB1, oqxB, oqxA, dfrA14, sul2, fosA, catB3, tet(A) | ColKP3, IncFII(K) |
Mero D6 = 6th day of meropenem therapy; Mero D4 = 4th day of meropenem therapy, A = AMP-AMC-TZP-CXM-CXM-AX-FOX-CTX-CAZ-FEP-ERTA-IPM-MEM-CIP-NIT-SXT; B = AMP-AMC-TZP-CXM-CXM-AX-FOX-CTX-CAZ-FEP-ERTA-MEM-CIP-NIT-SXT; C = AMP-AMC-TZP-CXM-CXM-AX-FOX-CTX-CAZ-FEP-ERTA-MEM-GEN-CIP-NIT-SXT.