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. 2021 Jul 16;10(7):1804. doi: 10.3390/cells10071804

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Post-mortem evaluation of GRPs’ graft localization in DBA1 semiallogenic model without immunosuppression applied: Immunohistochemical staining in the brain of DBA1 (semiallogenic) mice after 140 days of observation in a group with no immunosuppression applied. The staining revealed murine GRP GFP+ cells residing in the hippocampus, mostly in regio superior. Grafted cells were present close to MCP-1+ immune cells (A,B), as well as microglial cells (TMEM119+) (C,D). No CD45+ cells were visible in the adjacent tissues (E,F). Abbreviations: GFP-green fluorescent protein; GRP-glial-restricted progenitor cell.