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. 2021 Jun 29;11(7):1704. doi: 10.3390/nano11071704

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Expression levels of MGMT, E2F6, and RELA genes. (a) MGMT mRNA level significantly increased in TMZ treatment cells vs. untreated group. Treatment with Se@TMZ-Eud and Se@TMZ-Eud-Cs decreased MGMT significantly. (b) RELA mRNA level significantly reduced in Se@TMZ-Eud- and Se@TMZ-Eud-Cs-treated groups vs. TMZ-treated group. (c) E2F6 mRNA level significantly increased with Se@TMZ-Eud and decreased with Se@TMZ-Eud-Cs vs. TMZ-treated group. Data are presented as mean ± SD, n = 3. * p < 0.05 and ** p < 0.01.