Profile of this randomized clinical trial. The Early Childhood Education Center (CMEI) that received allocation for multiple micronutrients powder (MNP) in a health district had its peer in the same health district receiving ferrous sulphate and folic acid (FS_FA), defined by lot, totaling 10 CMEIs (5 MNP and 5 FS_FA). Within each of these CMEIs, if children were anaemic, they received the dose corresponding to the anaemia treatment recommendation, and if they were not anaemic, they received the dose corresponding to the prevention of anaemia. The number of children included in the intention-to-treat analysis corresponded to those for whom initial and final hemoglobin levels were measured.