Table 4.
Incidence of symptoms and infections with AAF-Syn vs. AAF as the proportion of infants affected and rate per person-year.
| AAF-Syn (n = 74) | AAF (n = 74) | p-Value | ||
|---|---|---|---|---|
| Symptoms | ||||
| GI symptoms | Proportion | 23% | 46% | 0.006 |
| Rate | 0.43 | 0.72 | 0.013 | |
| Skin symptoms | Proportion | 11% | 26% | 0.033 |
| Rate | 0.17 | 0.32 | 0.066 | |
| Respiratory symptoms | Proportion | 0% | 2.7% | 0.5 |
| Rate | 0 | 0.02 | 0.5 | |
| Infections | ||||
| GI infections | Proportion | 0 | 7% | 0.058 |
| Rate | 0 | 0.10 | 0.004 | |
| Skin infections | Proportion | 26% | 36% | 0.2 |
| Rate | 0.26 | 0.44 | 0.056 | |
| Respiratory infections | Proportion | 59% | 84% | 0.002 |
| Rate | 1.46 | 2.16 | <0.001 | |
| Ear infections | Proportion | 11% | 11% | >0.9 |
| Rate | 0.10 | 0.10 | >0.9 | |
AAF-Syn: amino acid formula with synbiotics; AAF: amino acid formula.